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Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains

G-quadruplexes (G4s), which are structures formed in guanine-rich regions of DNA, are involved in a variety of significant biological functions, and therefore “sequence-dependent” selective G4-stabilizing agents are required as tools to investigate and modulate these functions. Here, we describe the...

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Detalles Bibliográficos
Autores principales: Ma, Yue, Iida, Keisuke, Sasaki, Shogo, Hirokawa, Takatsugu, Heddi, Brahim, Phan, Anh Tuân, Nagasawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358838/
https://www.ncbi.nlm.nih.gov/pubmed/30642002
http://dx.doi.org/10.3390/molecules24020263