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Ciprofloxacin Enhances the Chemosensitivity of Cancer Cells to ABCB1 Substrates

ABCB1 is one of the major drug efflux transporters that is known to cause multidrug resistance (MDR) in cancer patients receiving chemotherapy for the treatment of solid tumors and hematological malignancies. Inhibition of ABCB1 efflux function is important for maintaining the intracellular concentr...

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Detalles Bibliográficos
Autores principales: Gupta, Pranav, Gao, Hai-Ling, Ashar, Yunali V., Karadkhelkar, Nishant M., Yoganathan, Sabesan, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358874/
https://www.ncbi.nlm.nih.gov/pubmed/30641875
http://dx.doi.org/10.3390/ijms20020268