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A Novel Synthetic Steroid of 2β,3α,5α-Trihydroxy-androst-6-one Alleviates the Loss of Rat Retinal Ganglion Cells Caused by Acute Intraocular Hypertension via Inhibiting the Inflammatory Activation of Microglia

Neuroinflammation has been well recognized as a key pathological event in acute glaucoma. The medical therapy of acute glaucoma mainly focuses on lowering intraocular pressure (IOP), while there are still scarce anti-inflammatory agents in the clinical treatment of acute glaucoma. Here we reported t...

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Detalles Bibliográficos
Autores principales: Sun, Hong-Jia-Qi, Xue, Dong-Dong, Lu, Bing-Zheng, Li, Yuan, Sheng, Long-Xiang, Zhu, Zhu, Zhou, Yu-Wei, Zhang, Jing-Xia, Lin, Gan-Jian, Lin, Sui-Zhen, Yan, Guang-Mei, Chen, Yu-Pin, Yin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358879/
https://www.ncbi.nlm.nih.gov/pubmed/30641903
http://dx.doi.org/10.3390/molecules24020252