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Transungual Delivery of Ciclopirox Is Increased 3–4-Fold by Mechanical Fenestration of Human Nail Plate in an In Vitro Model

Onychomycosis is a fungal infection of nails that is widespread and difficult to treat because of the impermeable nature of human nails. Topically applied anti-fungal agents cannot penetrate this structure, and treatment regimens often resort to systemic antifungals with concomitant side effects. On...

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Detalles Bibliográficos
Autores principales: Cordoba Díaz, Damian, Losa Iglesias, Marta Elena, Becerro de Bengoa Vallejo, Ricardo, Cordoba Diaz, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358885/
https://www.ncbi.nlm.nih.gov/pubmed/30646496
http://dx.doi.org/10.3390/pharmaceutics11010029