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Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling

Apelin is an inotropic and cardioprotective peptide that exhibits beneficial effects through activation of the APJ receptor in the pathology of cardiovascular diseases. Apelin induces the expression of angiotensin-converting enzyme 2 (ACE2) in failing hearts, thereby improving heart function in an a...

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Detalles Bibliográficos
Autores principales: Sato, Teruki, Kadowaki, Ayumi, Suzuki, Takashi, Ito, Hiroshi, Watanabe, Hiroyuki, Imai, Yumiko, Kuba, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358887/
https://www.ncbi.nlm.nih.gov/pubmed/30634441
http://dx.doi.org/10.3390/ijms20020239