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Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling
Apelin is an inotropic and cardioprotective peptide that exhibits beneficial effects through activation of the APJ receptor in the pathology of cardiovascular diseases. Apelin induces the expression of angiotensin-converting enzyme 2 (ACE2) in failing hearts, thereby improving heart function in an a...
Autores principales: | Sato, Teruki, Kadowaki, Ayumi, Suzuki, Takashi, Ito, Hiroshi, Watanabe, Hiroyuki, Imai, Yumiko, Kuba, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358887/ https://www.ncbi.nlm.nih.gov/pubmed/30634441 http://dx.doi.org/10.3390/ijms20020239 |
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