Formulation and Characterization of Eplerenone Nanoemulsion Liquisolids, An Oral Delivery System with Higher Release Rate and Improved Bioavailability

Because Eplerenone (EPL) is a Biopharmaceutical Classification System (BCS) class-II drug and is prone to extensive liver degradation, it suffers from poor bioavailability after oral administration. This work aimed to prepare liquisolids loaded with EPL-nanoemulsions (EPL-NEs) that have a higher dru...

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Detalles Bibliográficos
Autor principal: Khames, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358907/
https://www.ncbi.nlm.nih.gov/pubmed/30669353
http://dx.doi.org/10.3390/pharmaceutics11010040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358907/
https://www.ncbi.nlm.nih.gov/pubmed/30669353
http://dx.doi.org/10.3390/pharmaceutics11010040

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