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Production of a Novel Tetrahydroxynaphthalene (THN) Derivative from Nocardia sp. CS682 by Metabolic Engineering and Its Bioactivities

Nargenicin A1 is major secondary metabolite produced by Nocardia sp. CS682, with an effective antibacterial activity against various Gram-positive bacteria. Most Nocardia spp. have metabolic ability to produce compounds of diverse nature, so one-strain-many-compounds (OSMAC) approach can be applied...

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Detalles Bibliográficos
Autores principales: Mishra, Ravindra, Dhakal, Dipesh, Han, Jang Mi, Lim, Haet Nim, Jung, Hye Jin, Yamaguchi, Tokutaro, Sohng, Jae Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358914/
https://www.ncbi.nlm.nih.gov/pubmed/30634706
http://dx.doi.org/10.3390/molecules24020244