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Production of a Novel Tetrahydroxynaphthalene (THN) Derivative from Nocardia sp. CS682 by Metabolic Engineering and Its Bioactivities
Nargenicin A1 is major secondary metabolite produced by Nocardia sp. CS682, with an effective antibacterial activity against various Gram-positive bacteria. Most Nocardia spp. have metabolic ability to produce compounds of diverse nature, so one-strain-many-compounds (OSMAC) approach can be applied...
Autores principales: | Mishra, Ravindra, Dhakal, Dipesh, Han, Jang Mi, Lim, Haet Nim, Jung, Hye Jin, Yamaguchi, Tokutaro, Sohng, Jae Kyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358914/ https://www.ncbi.nlm.nih.gov/pubmed/30634706 http://dx.doi.org/10.3390/molecules24020244 |
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