Optimization of the Factors Affecting the Absorption of Vardenafil from Oral Disintegrating Tablets: A Clinical Pharmacokinetic Investigation

Because of poor solubility and considerable metabolism, vardenafil (VRD) bioavailability is 15%. To overcome this obstacle, this study aimed to increase the solubility, hasten the onset of action, and mask the unpleasant taste of VRD utilizing β-cyclodextrin (β-CD) and formulation of the inclusion c...

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Detalles Bibliográficos
Autores principales: Al-Gethmy, Hytham A., Fahmy, Usama A., Alhakamy, Nabil A., Ahmed, Osama A. A., El-Say, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358952/
https://www.ncbi.nlm.nih.gov/pubmed/30609647
http://dx.doi.org/10.3390/pharmaceutics11010011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358952/
https://www.ncbi.nlm.nih.gov/pubmed/30609647
http://dx.doi.org/10.3390/pharmaceutics11010011

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