Effects of Piperazine Derivative on Paclitaxel Pharmacokinetics

Paclitaxel (PTX) is an anticancer agent that is used to treat many cancers but it has a very low oral bioavailability due, at least in part, to the drug efflux transporter, P-glycoprotein (P-gp). Therefore, this study was performed to enhance oral bioavailability of PTX. In this study, we investigat...

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Detalles Bibliográficos
Autores principales: Lee, Jaeok, Chae, Song Wha, Oh, A Reum, Yoo, Ji Hye, Park Choo, Hea-Young, Rhie, Sandy Jeong, Lee, Hwa Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359037/
https://www.ncbi.nlm.nih.gov/pubmed/30626065
http://dx.doi.org/10.3390/pharmaceutics11010023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359037/
https://www.ncbi.nlm.nih.gov/pubmed/30626065
http://dx.doi.org/10.3390/pharmaceutics11010023

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