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Pharmacokinetics, Tissue Distribution, Plasma Protein Binding Studies of 10-Dehydroxyl-12-Demethoxy-Conophylline, a Novel Anti-Tumor Candidate, in Rats

10-Dehydroxyl-12-demethoxy-conophylline is a natural anticancer candidate. The motivation of this study was to explore the pharmacokinetic profiles, tissue distribution, and plasma protein binding of 10-dehydroxyl-12-demethoxy-conophylline in Sprague Dawley rats. A rapid, sensitive, and specific ult...

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Detalles Bibliográficos
Autores principales: Jiang, Chengjun, Li, Jie, Cai, Xianghai, Li, Nini, Guo, Yan, Wang, Dianlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359039/
https://www.ncbi.nlm.nih.gov/pubmed/30646543
http://dx.doi.org/10.3390/molecules24020283