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Intranasal Delivery of Genistein-Loaded Nanoparticles as a Potential Preventive System against Neurodegenerative Disorders

Genistein has been reported to have antioxidant and neuroprotective activity. Despite encouraging in vitro and in vivo results, several disadvantages such as poor water solubility, rapid metabolism, and low oral bioavailability limit the clinical application of genistein. The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Rassu, Giovanna, Porcu, Elena Piera, Fancello, Silvia, Obinu, Antonella, Senes, Nina, Galleri, Grazia, Migheli, Rossana, Gavini, Elisabetta, Giunchedi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359056/
https://www.ncbi.nlm.nih.gov/pubmed/30597930
http://dx.doi.org/10.3390/pharmaceutics11010008