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Intranasal Delivery of Genistein-Loaded Nanoparticles as a Potential Preventive System against Neurodegenerative Disorders
Genistein has been reported to have antioxidant and neuroprotective activity. Despite encouraging in vitro and in vivo results, several disadvantages such as poor water solubility, rapid metabolism, and low oral bioavailability limit the clinical application of genistein. The aim of this study was t...
Autores principales: | Rassu, Giovanna, Porcu, Elena Piera, Fancello, Silvia, Obinu, Antonella, Senes, Nina, Galleri, Grazia, Migheli, Rossana, Gavini, Elisabetta, Giunchedi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359056/ https://www.ncbi.nlm.nih.gov/pubmed/30597930 http://dx.doi.org/10.3390/pharmaceutics11010008 |
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