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Brain-Derived Neurotrophin and TrkB in Head and Neck Squamous Cell Carcinoma

We hypothesized that in head and neck squamous cell carcinoma (HNSCC), the neurotrophin brain-derived neurotrophic factor (BDNF) and its high affinity receptor TrkB regulate tumor cell survival, invasion, and therapy resistance. We used in situ hybridization for BDNF and immunohistochemistry (IHC) f...

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Detalles Bibliográficos
Autores principales: Dudás, József, Riml, Anna, Tuertscher, Raphaela, Pritz, Christian, Steinbichler, Teresa Bernadette, Schartinger, Volker Hans, Sprung, Susanne, Glueckert, Rudolf, Schrott-Fischer, Anneliese, Johnson Chacko, Lejo, Riechelmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359060/
https://www.ncbi.nlm.nih.gov/pubmed/30641914
http://dx.doi.org/10.3390/ijms20020272