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Complexes of Pro-Apoptotic siRNAs and Carbosilane Dendrimers: Formation and Effect on Cancer Cells

This paper examines the complexation of anti-cancer small interfering RNAs (siRNAs) by cationic carbosilane dendrimers, and the interaction of the formed complexes with HeLa and HL-60 cancer cells. Stepwise formation of the complexes accompanied by the evolution of their properties has been observed...

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Detalles Bibliográficos
Autores principales: Krasheninina, Olga A., Apartsin, Evgeny K., Fuentes, Elena, Szulc, Aleksandra, Ionov, Maksim, Venyaminova, Alya G., Shcharbin, Dzmitry, de la Mata, F. Javier, Bryszewska, Maria, Gόmez, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359069/
https://www.ncbi.nlm.nih.gov/pubmed/30634643
http://dx.doi.org/10.3390/pharmaceutics11010025