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Histone Deacetylation Inhibitors as Therapy Concept in Sepsis

Sepsis is characterized by dysregulated gene expression, provoking a hyper-inflammatory response occurring in parallel to a hypo-inflammatory reaction. This is often associated with multi-organ failure, leading to the patient’s death. Therefore, reprogramming of these pro- and anti-inflammatory, as...

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Detalles Bibliográficos
Autores principales: von Knethen, Andreas, Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359123/
https://www.ncbi.nlm.nih.gov/pubmed/30654448
http://dx.doi.org/10.3390/ijms20020346