Curcumin and Solid Lipid Curcumin Particles Induce Autophagy, but Inhibit Mitophagy and the PI3K-Akt/mTOR Pathway in Cultured Glioblastoma Cells

Autophagy and the (PI3K-Akt/mTOR) signaling pathway play significant roles in glioblastoma multiforme (GBM) cell death and survival. Curcumin (Cur) has been reported to prevent several cancers, including GBM. However, the poor solubility and limited bioavailability of natural Cur limits its applicat...

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Detalles Bibliográficos
Autores principales: Maiti, Panchanan, Scott, Jason, Sengupta, Dipanwita, Al-Gharaibeh, Abeer, Dunbar, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359162/
https://www.ncbi.nlm.nih.gov/pubmed/30669284
http://dx.doi.org/10.3390/ijms20020399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359162/
https://www.ncbi.nlm.nih.gov/pubmed/30669284
http://dx.doi.org/10.3390/ijms20020399

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