Symmetrical Heterocyclic Cage Skeleton: Synthesis, Urease Inhibition Activity, Kinetic Mechanistic Insight, and Molecular Docking Analyses

The present study focuses on the design and synthesis of a cage-like organic skeleton containing two triazole rings jointed via imine linkage. These molecules can act as urease inhibitors. The in-vitro urease inhibition screening results showed that the combination of the two triazole skeleton in th...

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Detalles Bibliográficos
Autores principales: Hanif, Muhammad, Kanwal, Fariha, Rafiq, Muhammad, Hassan, Mubashir, Mustaqeem, Muhammad, Seo, Sung-Yum, Zhang, Yunlong, Lu, Changrui, Chen, Ting, Saleem, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359172/
https://www.ncbi.nlm.nih.gov/pubmed/30654516
http://dx.doi.org/10.3390/molecules24020312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359172/
https://www.ncbi.nlm.nih.gov/pubmed/30654516
http://dx.doi.org/10.3390/molecules24020312

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