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Fabrication, Optimization, and Evaluation of Rotigotine-Loaded Chitosan Nanoparticles for Nose-To-Brain Delivery

The objective of the present study was to develop, optimize, and evaluate rotigotine-loaded chitosan nanoparticles (RNPs) for nose-to-brain delivery. Rotigotine-loaded chitosan nanoparticles were prepared by the ionic gelation method and optimized for various parameters such as the effect of chitosa...

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Detalles Bibliográficos
Autores principales: Tzeyung, Angeline Shak., Md, Shadab, Bhattamisra, Subrat Kumar, Madheswaran, Thiagarajan, Alhakamy, Nabil A., Aldawsari, Hibah M., Radhakrishnan, Ammu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359179/
https://www.ncbi.nlm.nih.gov/pubmed/30634665
http://dx.doi.org/10.3390/pharmaceutics11010026