Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism

Many new chemical entities are discovered with high therapeutic potential, however, many of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility and/or poor membrane permeation characteristics. The latter is mainly due to the lipid-like barrier imposed by epithelial...

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Detalles Bibliográficos
Autores principales: Peterson, Bianca, Weyers, Morné, Steenekamp, Jan H., Steyn, Johan D., Gouws, Chrisna, Hamman, Josias H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359194/
https://www.ncbi.nlm.nih.gov/pubmed/30654429
http://dx.doi.org/10.3390/pharmaceutics11010033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359194/
https://www.ncbi.nlm.nih.gov/pubmed/30654429
http://dx.doi.org/10.3390/pharmaceutics11010033

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