A New Approach for Improving the Antibacterial and Tumor Cytotoxic Activities of Pipemidic Acid by Including It in Trimethyl-β-cyclodextrin

Pipemidic acid (HPPA) is a quinolone antibacterial agent used mostly to treat gram-negative infections of the urinary tract, but its therapeutic use is limited because of its low solubility. Thus, to improve drug solubility, natural cyclodextrins (CDs) are used for their ability of including guest m...

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Detalles Bibliográficos
Autores principales: Lavorgna, Margherita, Iacovino, Rosa, Russo, Chiara, Di Donato, Cristina, Piscitelli, Concetta, Isidori, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359225/
https://www.ncbi.nlm.nih.gov/pubmed/30669399
http://dx.doi.org/10.3390/ijms20020416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359225/
https://www.ncbi.nlm.nih.gov/pubmed/30669399
http://dx.doi.org/10.3390/ijms20020416

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