Solid Lipid Nanoparticles Loading Idebenone Ester with Pyroglutamic Acid: In Vitro Antioxidant Activity and In Vivo Topical Efficacy

Idebenone (IDE), a strong antioxidant widely investigated for the treatment of neurodegenerative diseases and skin disorders, shows low oral and topical bioavailability due to its unfavorable physico-chemical properties. In this work, to improve IDE topical effectiveness, we explored a two-steps app...

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Detalles Bibliográficos
Autores principales: Montenegro, Lucia, Panico, Anna Maria, Santagati, Ludovica Maria, Siciliano, Edy Angela, Intagliata, Sebastiano, Modica, Maria N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359231/
https://www.ncbi.nlm.nih.gov/pubmed/30597985
http://dx.doi.org/10.3390/nano9010043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359231/
https://www.ncbi.nlm.nih.gov/pubmed/30597985
http://dx.doi.org/10.3390/nano9010043

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