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Solid Lipid Nanoparticles Loading Idebenone Ester with Pyroglutamic Acid: In Vitro Antioxidant Activity and In Vivo Topical Efficacy

Idebenone (IDE), a strong antioxidant widely investigated for the treatment of neurodegenerative diseases and skin disorders, shows low oral and topical bioavailability due to its unfavorable physico-chemical properties. In this work, to improve IDE topical effectiveness, we explored a two-steps app...

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Detalles Bibliográficos
Autores principales:	Montenegro, Lucia, Panico, Anna Maria, Santagati, Ludovica Maria, Siciliano, Edy Angela, Intagliata, Sebastiano, Modica, Maria N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359231/ https://www.ncbi.nlm.nih.gov/pubmed/30597985 http://dx.doi.org/10.3390/nano9010043

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