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Synthesis, In Vitro Screening and Docking Studies of New Thiosemicarbazide Derivatives as Antitubercular Agents

A series of thiosemicarbazide derivatives was designed and synthesized by reaction of carboxylic acid hydrazide with isothiocyanates. The molecular structures of the investigated thiosemicarbazides were confirmed and characterized by spectroscopic analysis. The conformational preference of carbonylt...

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Detalles Bibliográficos
Autores principales: Pitucha, Monika, Karczmarzyk, Zbigniew, Swatko-Ossor, Marta, Wysocki, Waldemar, Wos, Maciej, Chudzik, Kamil, Ginalska, Grazyna, Fruzinski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359303/
https://www.ncbi.nlm.nih.gov/pubmed/30641902
http://dx.doi.org/10.3390/molecules24020251