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Synthesis, In Vitro Screening and Docking Studies of New Thiosemicarbazide Derivatives as Antitubercular Agents
A series of thiosemicarbazide derivatives was designed and synthesized by reaction of carboxylic acid hydrazide with isothiocyanates. The molecular structures of the investigated thiosemicarbazides were confirmed and characterized by spectroscopic analysis. The conformational preference of carbonylt...
Autores principales: | Pitucha, Monika, Karczmarzyk, Zbigniew, Swatko-Ossor, Marta, Wysocki, Waldemar, Wos, Maciej, Chudzik, Kamil, Ginalska, Grazyna, Fruzinski, Andrzej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359303/ https://www.ncbi.nlm.nih.gov/pubmed/30641902 http://dx.doi.org/10.3390/molecules24020251 |
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