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Dual Role of Triptolide in Interrupting the NLRP3 Inflammasome Pathway to Attenuate Cardiac Fibrosis

In a previous paper, we reported that triptolide (TP), a commonly used immunomodulator, could attenuate cardiac hypertrophy. This present study aimed to further explore the inhibition of cardiac fibrosis by TP and the possible mechanism from the perspective of the NOD-like receptor protein 3 (NLRP3)...

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Detalles Bibliográficos
Autores principales: Pan, Xi-Chun, Liu, Ya, Cen, Yan-Yan, Xiong, Ya-Lan, Li, Jing-Mei, Ding, Yuan-Yuan, Tong, Yang-Fei, Liu, Tao, Chen, Xiao-Hong, Zhang, Hai-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359320/
https://www.ncbi.nlm.nih.gov/pubmed/30654511
http://dx.doi.org/10.3390/ijms20020360