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Delayed Chromosome Alignment to the Spindle Equator Increases the Rate of Chromosome Missegregation in Cancer Cell Lines

For appropriate chromosome segregation, kinetochores on sister chromatids have to attach to microtubules from opposite spindle poles (bi-orientation). Chromosome alignment at the spindle equator, referred to as congression, can occur through the attachment of kinetochores to the lateral surface of s...

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Detalles Bibliográficos
Autores principales: Kuniyasu, Kinue, Iemura, Kenji, Tanaka, Kozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359495/
https://www.ncbi.nlm.nih.gov/pubmed/30597919
http://dx.doi.org/10.3390/biom9010010