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Specialized Roles for Actin in Osteoclasts: Unanswered Questions and Therapeutic Opportunities
Osteoclasts are cells of the hematopoietic lineage that are specialized to resorb bone. In osteoclasts, the actin cytoskeleton engages in at least two unusual activities that are required for resorption. First, microfilaments form a dynamic and structurally elaborate actin ring. Second, microfilamen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359508/ https://www.ncbi.nlm.nih.gov/pubmed/30634501 http://dx.doi.org/10.3390/biom9010017 |