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Specialized Roles for Actin in Osteoclasts: Unanswered Questions and Therapeutic Opportunities

Osteoclasts are cells of the hematopoietic lineage that are specialized to resorb bone. In osteoclasts, the actin cytoskeleton engages in at least two unusual activities that are required for resorption. First, microfilaments form a dynamic and structurally elaborate actin ring. Second, microfilamen...

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Detalles Bibliográficos
Autores principales: Han, Guanghong, Zuo, Jian, Holliday, Lexie Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359508/
https://www.ncbi.nlm.nih.gov/pubmed/30634501
http://dx.doi.org/10.3390/biom9010017