Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity

To find novel antitumor agents, a series of 1H-benzofuro[3,2-c]pyrazole derivatives 4a-e were designed and synthesized. The treatment of 6-methoxybenzofuran-3(2H)-one 3 with LiHMDS in anhydrous tetrahydrofuran (THF) followed by reaction with 3-substitued phenyl isothiocyanate gave the thioamide inte...

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Detalles Bibliográficos
Autores principales: Cui, Ying-Jie, Tang, Long-Qian, Zhang, Cheng-Mei, Liu, Zhao-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359563/
https://www.ncbi.nlm.nih.gov/pubmed/30642134
http://dx.doi.org/10.3390/molecules24020279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359563/
https://www.ncbi.nlm.nih.gov/pubmed/30642134
http://dx.doi.org/10.3390/molecules24020279

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