The Crossroad of Ion Channels and Calmodulin in Disease

Calmodulin (CaM) is the principal Ca(2+) sensor in eukaryotic cells, orchestrating the activity of hundreds of proteins. Disease causing mutations at any of the three genes that encode identical CaM proteins lead to major cardiac dysfunction, revealing the importance in the regulation of excitabilit...

Descripción completa

Detalles Bibliográficos
Autores principales: Urrutia, Janire, Aguado, Alejandra, Muguruza-Montero, Arantza, Núñez, Eider, Malo, Covadonga, Casis, Oscar, Villarroel, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359610/
https://www.ncbi.nlm.nih.gov/pubmed/30669290
http://dx.doi.org/10.3390/ijms20020400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359610/
https://www.ncbi.nlm.nih.gov/pubmed/30669290
http://dx.doi.org/10.3390/ijms20020400

Ejemplares similares