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The Crossroad of Ion Channels and Calmodulin in Disease
Calmodulin (CaM) is the principal Ca(2+) sensor in eukaryotic cells, orchestrating the activity of hundreds of proteins. Disease causing mutations at any of the three genes that encode identical CaM proteins lead to major cardiac dysfunction, revealing the importance in the regulation of excitabilit...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359610/ https://www.ncbi.nlm.nih.gov/pubmed/30669290 http://dx.doi.org/10.3390/ijms20020400 |