Preparation of Messenger RNA Nanomicelles via Non-Cytotoxic PEG-Polyamine Nanocomplex for Intracerebroventicular Delivery: A Proof-of-Concept Study in Mouse Models

The specific delivery of messenger RNA (mRNA) is an excellent alternative to plasmid DNA, due to the latter’s potential risk for random integration into the host genome. In this study, we propose the use of specially tailored polyplex nanomicelles for the intravenous delivery of mRNA into the brain...

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Detalles Bibliográficos
Autores principales: Chan, Long Yi, Khung, Yit Lung, Lin, Chin-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359661/
https://www.ncbi.nlm.nih.gov/pubmed/30621291
http://dx.doi.org/10.3390/nano9010067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359661/
https://www.ncbi.nlm.nih.gov/pubmed/30621291
http://dx.doi.org/10.3390/nano9010067

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