Enhancing Stability of Destabilized Green Fluorescent Protein Using Chimeric mRNA Containing Human Beta-Globin 5′ and 3′ Untranslated Regions

BACKGROUND: In spite of recent progress in mRNA technologies and their potential applications for treatment of human diseases, problems such as the transient nature of mRNA limit the stability of gene up-regulation and, thus, potentially reduce mRNA efficiency for gene therapy. Using human β-globin...

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Detalles Bibliográficos
Autores principales: Adibzadeh, Setare, Fardaei, Majid, Takhshid, Mohammad Ali, Miri, Mohammad Reza, Rafiei Dehbidi, Gholamreza, Farhadi, Ali, Ranjbaran, Reza, Alavi, Parnian, Nikouyan, Negin, Seyyedi, Noorossadat, Naderi, Samaneh, Eskandari, Alireaz, Behzad-Behbahani, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359690/
https://www.ncbi.nlm.nih.gov/pubmed/30800251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359690/
https://www.ncbi.nlm.nih.gov/pubmed/30800251

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