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Enhancing Stability of Destabilized Green Fluorescent Protein Using Chimeric mRNA Containing Human Beta-Globin 5′ and 3′ Untranslated Regions
BACKGROUND: In spite of recent progress in mRNA technologies and their potential applications for treatment of human diseases, problems such as the transient nature of mRNA limit the stability of gene up-regulation and, thus, potentially reduce mRNA efficiency for gene therapy. Using human β-globin...
Autores principales: | Adibzadeh, Setare, Fardaei, Majid, Takhshid, Mohammad Ali, Miri, Mohammad Reza, Rafiei Dehbidi, Gholamreza, Farhadi, Ali, Ranjbaran, Reza, Alavi, Parnian, Nikouyan, Negin, Seyyedi, Noorossadat, Naderi, Samaneh, Eskandari, Alireaz, Behzad-Behbahani, Abbas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Avicenna Research Institute
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359690/ https://www.ncbi.nlm.nih.gov/pubmed/30800251 |
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