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HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance

Normal cells produce adenosine 5′-triphosphate (ATP) mainly through mitochondrial oxidative phosphorylation (OXPHOS) when oxygen is available. Most cancer cells, on the other hand, are known to produce energy predominantly through accelerated glycolysis, followed by lactic acid fermentation even und...

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Detalles Bibliográficos
Autores principales: Nagao, Ayako, Kobayashi, Minoru, Koyasu, Sho, Chow, Christalle C. T., Harada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359724/
https://www.ncbi.nlm.nih.gov/pubmed/30634433
http://dx.doi.org/10.3390/ijms20020238