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Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican population
BACKGROUND: Heterozygous germline TP53 gene mutations result in Li-Fraumeni Syndrome (LFS). Breast cancer (BC) is the most frequent tumor in young women with LFS. An important issue related to BC in the Mexican population is the average age at diagnosis, which is approximately 11 years younger than...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359755/ https://www.ncbi.nlm.nih.gov/pubmed/30709381 http://dx.doi.org/10.1186/s12885-019-5312-2 |