Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican population

BACKGROUND: Heterozygous germline TP53 gene mutations result in Li-Fraumeni Syndrome (LFS). Breast cancer (BC) is the most frequent tumor in young women with LFS. An important issue related to BC in the Mexican population is the average age at diagnosis, which is approximately 11 years younger than...

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Detalles Bibliográficos
Autores principales: Gallardo-Alvarado, Lenny N., Tusié-Luna, María Teresa, Tussié-Luna, María Isabel, Díaz-Chávez, José, Segura, Yayoi X., Bargallo-Rocha, Enrique, Villarreal, Cynthia, Herrera-Montalvo, Luis A., Herrera-Medina, Enrique M., Cantu-de Leon, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359755/
https://www.ncbi.nlm.nih.gov/pubmed/30709381
http://dx.doi.org/10.1186/s12885-019-5312-2

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