Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity

BACKGROUND: Escherichia coli W3110 and a group of six isogenic derivatives, each displaying distinct specific rates of glucose consumption were characterized to determine levels of GFP production and population heterogeneity. These strains have single or combinatory deletions in genes encoding phosp...

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Detalles Bibliográficos
Autores principales: Fragoso-Jiménez, Juan Carlos, Baert, Jonathan, Nguyen, Thai Minh, Liu, Wenzheng, Sassi, Hosni, Goormaghtigh, Frédéric, Van Melderen, Laurence, Gaytán, Paul, Hernández-Chávez, Georgina, Martinez, Alfredo, Delvigne, Frank, Gosset, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359759/
https://www.ncbi.nlm.nih.gov/pubmed/30710996
http://dx.doi.org/10.1186/s12934-019-1073-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359759/
https://www.ncbi.nlm.nih.gov/pubmed/30710996
http://dx.doi.org/10.1186/s12934-019-1073-5

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