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All-trans retinoic acid inhibits lipopolysaccharide-induced inflammatory responses in bovine adipocytes via TGFβ1/Smad3 signaling pathway

BACKGROUND: Dairy cows with metabolic disorder in peripartal period display high inflammatory levels. Adipose tissue is a major endocrine organ, which is closely related to systemic inflammation. Retinoic acid (RA), an active metabolite of vitamin A, has shown potential therapeutic immunomodulatory...

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Detalles Bibliográficos
Autores principales: Xu, Qiushi, Jia, Hongdou, Ma, Li, Liu, Guowen, Xu, Chuang, Li, Ying, Li, Xinwei, Li, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359792/
https://www.ncbi.nlm.nih.gov/pubmed/30709353
http://dx.doi.org/10.1186/s12917-019-1791-2