Cargando…

GSK-3β regulates the endothelial-to-mesenchymal transition via reciprocal crosstalk between NSCLC cells and HUVECs in multicellular tumor spheroid models

BACKGROUND: Chemotherapy used for patients with unresectable lung tumors remains largely palliative due to chemoresistance, which may be due to tumor heterogeneity. Recently, multiple studies on the crosstalk between lung cancer cells and their tumor microenvironment (TME) have been conducted to und...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Se-Hyuk, Song, Yeonhwa, Seo, Haeng Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359813/
https://www.ncbi.nlm.nih.gov/pubmed/30709379
http://dx.doi.org/10.1186/s13046-019-1050-1