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MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors

BACKGROUND: Non-coding RNAs and especially microRNAs have been discovered to act as master regulators of cancer initiation and progression. The aim of our study was to discover and characterize the function of yet functionally uncharacterized microRNAs in human breast carcinogenesis. METHODS: In an...

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Detalles Bibliográficos
Autores principales: Schwarzenbacher, Daniela, Klec, Christiane, Pasculli, Barbara, Cerk, Stefanie, Rinner, Beate, Karbiener, Michael, Ivan, Cristina, Barbano, Raffaela, Ling, Hui, Wulf-Goldenberg, Annika, Stanzer, Stefanie, Rinnerthaler, Gabriel, Stoeger, Herbert, Bauernhofer, Thomas, Haybaeck, Johannes, Hoefler, Gerald, Jahn, Stephan Wenzel, Parrella, Paola, Calin, George Adrian, Pichler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359814/
https://www.ncbi.nlm.nih.gov/pubmed/30709367
http://dx.doi.org/10.1186/s13058-019-1104-5