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CpG traffic lights are markers of regulatory regions in human genome

BACKGROUND: DNA methylation is involved in the regulation of gene expression. Although bisulfite-sequencing based methods profile DNA methylation at a single CpG resolution, methylation levels are usually averaged over genomic regions in the downstream bioinformatic analysis. RESULTS: We demonstrate...

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Detalles Bibliográficos
Autores principales: Lioznova, Anna V., Khamis, Abdullah M., Artemov, Artem V., Besedina, Elizaveta, Ramensky, Vasily, Bajic, Vladimir B., Kulakovskiy, Ivan V., Medvedeva, Yulia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359853/
https://www.ncbi.nlm.nih.gov/pubmed/30709331
http://dx.doi.org/10.1186/s12864-018-5387-1