Comparative AAV-eGFP Transgene Expression Using Vector Serotypes 1–9, 7m8, and 8b in Human Pluripotent Stem Cells, RPEs, and Human and Rat Cortical Neurons

Recombinant adeno-associated virus (rAAV), produced from a nonpathogenic parvovirus, has become an increasing popular vector for gene therapy applications in human clinical trials. However, transduction and transgene expression of rAAVs can differ across in vitro and ex vivo cellular transduction st...

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Detalles Bibliográficos
Autores principales: Duong, Thu T., Lim, James, Vasireddy, Vidyullatha, Papp, Tyler, Nguyen, Hung, Leo, Lanfranco, Pan, Jieyan, Zhou, Shangzhen, Chen, H. Isaac, Bennett, Jean, Mills, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360060/
https://www.ncbi.nlm.nih.gov/pubmed/30800164
http://dx.doi.org/10.1155/2019/7281912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360060/
https://www.ncbi.nlm.nih.gov/pubmed/30800164
http://dx.doi.org/10.1155/2019/7281912

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