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Exendin-4 Exacerbates Burn-Induced Morbidity in Mice by Activation of the Sympathetic Nervous System

BACKGROUND: Although glucagon-like peptide 1- (GLP-1-) based therapy of hyperglycemia in burn injury has shown great potential in clinical trials, its safety is seldom evaluated. We hypothesize that exendin-4, a GLP-1 analogue, might affect the immune response via the activation of the sympathetic n...

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Detalles Bibliográficos
Autores principales: Ji, Xiao-Jing, Hao, Ji-Wei, Li, Guang-Lei, Dong, Ning, Wang, Xin-Qi, Zhou, Min, Zhang, Qing-Hong, Yao, Yong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360064/
https://www.ncbi.nlm.nih.gov/pubmed/30800001
http://dx.doi.org/10.1155/2019/2750528