Treatment With Naringenin Elevates the Activity of Transcription Factor Nrf2 to Protect Pancreatic β-Cells From Streptozotocin-Induced Diabetes in vitro and in vivo

Chronic hyperglycemia and unusually high oxidative stress are the key contributors for diabetes in humans. Since nuclear factor E2-related factor 2 (Nrf2) controls the expression of antioxidant- and detoxification genes, it is hypothesized that targeted activation of Nrf2 using phytochemicals is lik...

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Detalles Bibliográficos
Autores principales: Rajappa, Rashmi, Sireesh, Dornadula, Salai, Magesh B., Ramkumar, Kunka M., Sarvajayakesavulu, Suryanarayanan, Madhunapantula, SubbaRao V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360183/
https://www.ncbi.nlm.nih.gov/pubmed/30745874
http://dx.doi.org/10.3389/fphar.2018.01562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360183/
https://www.ncbi.nlm.nih.gov/pubmed/30745874
http://dx.doi.org/10.3389/fphar.2018.01562

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