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A PDZ Protein MDA-9/Syntenin: As a Target for Cancer Therapy

Melanoma differentiation-associated gene 9 (MDA-9)/Syntenin is a multidomain PDZ protein and identified as a key oncogene in melanoma initially. This protein contains a unique tandem PDZ domain architecture (PDZ1 and PDZ2 spaced by a 4-amino acid linker), an N-terminal domain (NTD) that is structura...

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Detalles Bibliográficos
Autores principales: Yu, Yongsheng, Li, Shuangdi, Wang, Kai, Wan, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360254/
https://www.ncbi.nlm.nih.gov/pubmed/30766662
http://dx.doi.org/10.1016/j.csbj.2019.01.002