Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway

BACKGROUND: Chondrosarcomas are malignant cartilage-producing tumors showing mutations and changes in gene expression in metabolism related genes. In this study, we aimed to explore the metabolome and identify targetable metabolic vulnerabilities in chondrosarcoma. METHODS: A custom-designed metabol...

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Detalles Bibliográficos
Autores principales: Addie, Ruben D., de Jong, Yvonne, Alberti, Gaia, Kruisselbrink, Alwine B., Que, Ivo, Baelde, Hans, Bovée, Judith V.M.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360255/
https://www.ncbi.nlm.nih.gov/pubmed/30766792
http://dx.doi.org/10.1016/j.jbo.2019.100222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360255/
https://www.ncbi.nlm.nih.gov/pubmed/30766792
http://dx.doi.org/10.1016/j.jbo.2019.100222

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