Growth Factor–like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells

Recurrent mutational activation of the MAP kinase pathway in plasma cell myeloma implicates growth factor–like signaling responses in the biology of Ab-secreting cells (ASCs). Physiological ASCs survive in niche microenvironments, but how niche signals are propagated and integrated is poorly underst...

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Detalles Bibliográficos
Autores principales: Stephenson, Sophie, Care, Matthew A., Fan, Im, Zougman, Alexandre, Westhead, David R., Doody, Gina M., Tooze, Reuben M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2019
Materias:
Systems Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360259/
https://www.ncbi.nlm.nih.gov/pubmed/30642980
http://dx.doi.org/10.4049/jimmunol.1801407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360259/
https://www.ncbi.nlm.nih.gov/pubmed/30642980
http://dx.doi.org/10.4049/jimmunol.1801407

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