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Amlexanox and UPF1 Modulate Wnt Signaling and Apoptosis in HCT-116 Colorectal Cancer Cells
Deregulated Wnt signaling initiates most cases of colorectal cancer (CRC). Butyrate, a product of dietary fiber, hyperactivates Wnt signaling, resulting in induction of CRC cell apoptosis, which may in part explain the protective action of fiber. Nonsense mediated decay (NMD) of mRNAs containing pre...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360298/ https://www.ncbi.nlm.nih.gov/pubmed/30719122 http://dx.doi.org/10.7150/jca.28331 |